AL Goldin - Methods in cell biology, 1991 - Elsevier
Publisher Summary This chapter briefly outlines the approaches and methods used for
expression of ion channels by injection of messenger RNA (mRNA) into Xenopus oocytes.
The Xenopus oocyte system is perhaps uniquely suited to the study of ion channels and
neural receptors in a controlled in vivo environment. The oocyte system is used as an assay
for the isolation of complementary DNA (cDNA) clones encoding receptors for which the only
information available was a functional response. The oocyte expression system is …