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CG Woods, J Cox, K Springell, DJ Hampshire… - The American Journal of …, 2006 - Elsevier
Individuals born of consanguineous union have segments of their genomes that are
homozygous as a result of inheriting identical ancestral genomic segments through both
parents. One consequence of this is an increased incidence of recessive disease within
these sibships. Theoretical calculations predict that 6%(1/16) of the genome of a child of first
cousins will be homozygous and that the average homozygous segment will be 20 cM in
size. We assessed whether these predictions held true in populations that have preferred …