D Buergy, F Wenz, C Groden… - International journal of …, 2012 - Wiley Online Library
Elevated platelet counts in patients diagnosed with malignant tumors were first described
more than 100 years ago. Today it is well known that in many types of solid tumors,
thrombocytosis at the time of diagnosis is associated with shorter survival. From this well‐
documented clinical correlation between platelet count and prognosis of solid tumors, the
following questions arise:(i) Are the increased platelet counts the reason for shortened
survival as platelet‐secreted cytokines might boost tumor growth and angiogenesis?(ii) Do …