D Johansson, O Shannon, M Rasmussen - PloS one, 2011 - journals.plos.org
Background Many Gram-positive pathogens aggregate and activate platelets in vitro and
this has been proposed to contribute to virulence. Platelets can also form complexes with
neutrophils but little is however known about platelet and platelet-neutrophil responses in
bacterial infection. Methodology/Principal Findings We added isolates of Gram-positive
bacteria from 38 patients with a bacteremic infection to blood drawn from the same patient.
Aggregometry and flow cytometry were used to assess platelet aggregation and to quantify …