EM Pieczarka, M Yamaguchi… - Veterinary clinical …, 2014 - Wiley Online Library
A 13‐year‐old neutered male English Springer Spaniel was presented to The Ohio State
University Veterinary Medical Center for evaluation of severe anemia. Upon blood smear
review, approximately 50% of the platelets contained single to multiple variably sized clear
vacuoles. Transmission electron microscopy of the platelets revealed hallmark features of
autophagy, including membrane‐lined vesicles and vacuoles containing membrane whorls
and degrading organelles. While autophagy has been demonstrated in a wide range of …