M Schmolke, A García‐Sastre - Cellular microbiology, 2010 - Wiley Online Library
Host organisms have developed sophisticated antiviral responses in order to defeat
emerging influenza A viruses (IAVs). At the same time IAVs have evolved immune evasion
strategies. The immune system of mammals provides several lines of defence to neutralize
invading pathogens or limit their replication. Here, we summarize the mammalian innate and
adaptive immune mechanisms involved in host defence against viral infection and review
strategies by which IAVs avoid, circumvent or subvert these mechanisms. We highlight well …