M Jansson, M Popovic, A Karlsson… - Proceedings of the …, 1996 - National Acad Sciences
Primary HIV-1 isolates were evaluated for their sensitivity to inhibition by β-chemokines
RANTES (regulated upon activation, normal T-cell expressed and secreted), macrophage
inflammatory protein 1α (MIP-1α), and MIP-1β. Virus isolates of both nonsyncytium-inducing
(NSI) and syncytium-inducing (SI) biological phenotypes recovered from patients at various
stages of HIV-1 infection were assessed, and the results indicated that only the isolates with
the NSI phenotype were substantially inhibited by the β-chemokines. More important to note …