S Sarkar - FEBS letters, 1998 - Wiley Online Library
Platelet aggregation is accompanied by the tyrosine phosphorylation of several proteins
including syk. However, some of these proteins are not identified. Recent studies showed
that LAT is a syk substrate and is tyrosine phosphorylated during T cell stimulation. In this
study, we demonstrated that LAT is present in platelets and is tyrosine phosphorylated in
response to ADP‐and thrombin‐stimulated aggregation. Moreover, LAT, like syk and β3,
translocates to the cytoskeleton during the late stage of thrombin‐stimulated irreversible …