T Sugiyama, M Okuma, F Ushikubi, S Sensaki… - Blood, 1987 - Am Soc Hematology
We found a novel platelet aggregating factor in a patient with steroid-responsive immune
thrombocytopenic purpura that is associated with defective collagen-induced platelet
functions. The aggregating factor and platelet functions were analyzed. The patient, a 58-
year-old female, had purpura and prolonged bleeding time despite adequate platelet counts
(greater than 140,000/microL) after steroid therapy. The patient9s platelets responded
normally to all agonists except collagen. Platelet adhesion to collagen fibrils was decreased …