…, Y Matsuo, MR Lieber, H Mizoguchi, J Yokota… - Journal of Biological …, 2002 - ASBMB
To understand molecular pathways underlying 9p21 deletions, which lead to inactivation of
the p16/CDKN2A, p14/ARF, and/or p15/CDKN2B genes, in lymphoid leukemia, 30
breakpoints were cloned from 15 lymphoid leukemia cell lines. Seventeen (57%) …


…, M Yi, RM Stephens, A Okamoto, J Yokota… - Cancer cell, 2006 - Elsevier
MicroRNA (miRNA) expression profiles for lung cancers were examined to investigate
miRNA's involvement in lung carcinogenesis. miRNA microarray analysis identified
statistical unique profiles, which could discriminate lung cancers from noncancerous lung …

…, S Ogawa, CC Harris, H Tsuda, T Yoshida, J Yokota… - Nature medicine, 2012 - nature.com
We identified in-frame fusion transcripts of KIF5B (the kinesin family 5B gene) and the RET
oncogene, which are present in 1–2% of lung adenocarcinomas (LADCs) from people from
Japan and the United States, using whole-transcriptome sequencing. The KIF5B-RET fusion …

C Caldas, F Carneiro, HT Lynch, J Yokota… - Journal of medical …, 1999 - jmg.bmj.com
Families with autosomal dominant inherited predisposition to gastric cancer have been
described. More recently, germlineE-cadherin/CDH1mutations have been identified in
hereditary diffuse gastric cancer kindred. The need to have protocols to manage and …

J Yokota, M Wada, Y Shimosato… - Proceedings of the …, 1987 - National Acad Sciences
By a molecular genetic approach using polymorphic DNA markers that detect allelic deletion
of specific chromosomal regions, we analyzed for possible loss of chromosomal
heterozygosity in five different histological types of lung cancers obtained from 47 patients …

…, SR Kim, H Sugimura, T Nohmi, H Kasai, J Yokota - Oncogene, 1998 - nature.com
The hOGG1 gene encodes a DNA glycosylase that excises 8-hydroxyguanine (oh 8 Gua)
from damaged DNA. Structural analyses of the hOGG1 gene and its transcripts were
performed in normal and lung cancer cells. Due to a genetic polymorphism at codon 326 …

…, B Pinther, P Schaub, C Becker, J Altmüller, J Yokota… - Nature, 2015 - nature.com
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the
deadliest human cancers. In nearly all the tumours analysed we found bi-allelic inactivation
of TP53 and RB1, sometimes by complex genomic rearrangements. Two tumours with wild …

…, M Teranaka, J Yamato, H Okabe, J Yokota… - Physical review …, 1986 - APS
We have located 3886 neutrino interactions in the fiducial volume of a hybrid emulsion
spectrometer installed in the Fermilab wide-band neutrino beam. A search for τ− decays
yielded no candidate, resulting in an upper limit of 0.002 (0.073) for direct coupling of ν μ (ν …

Y Shinoda, JI Yokota, T Futami - Neuroscience letters, 1981 - Elsevier
Intracellular staining with horseradish peroxidase (HRP) of physiologically identified
corticospinal (CS) axons originating from the monkey motor cortex revealed the intraspinal
morphology of their branching patterns. CS collaterals spread in a delta-like fashion in the …

J Yokota, Y Tsunetsugu-Yokota, H Battifora… - …, 1986 - science.sciencemag.org
Alterations of c-myc, c-rasHa, or c-myb oncogenes were found in more than one-third of
human solid tumors. Amplification of c-myc occurred in advanced, widespread tumors or in
aggressive primary tumors. Apparent allelic deletions of c-rasHa and c-myb can be …